Pediamont LC Kid Syrup

Description

Therapy / Class

Levocetirizine

Therapy: Anti-Allergic

Class: Second Generation Antihistamines

Montelukast

Therapy: Anti-Allergic

Class: Leukotriene receptor antagonist (LTRA)

Mechanism of Action

Levocetirizine:It is a highly selective for histamine H1-receptors & competes with free histamine for binding at H1-receptor sites. This competitive antagonism blocks the effects of histamine on H1-receptors in the GI tract, large blood vessels, and bronchial smooth muscle. Blockade of H1-receptors also suppresses the formation of edema, flare, and pruritus that result from histaminic activity. It also has anti-inflammatory action related to a reduction in eosinophils, neutrophils, interleukin-4 and interleukin-8.

Montelukast:It bind & act as antagonists to cysteinyl leukotriene (CysLT) receptor found in the human airway including airway smooth muscle cells and airway macrophages. CysLTs have been correlated with the pathophysiology of asthma and allergic rhinitis.

Indications

• Alleviation of symptoms associated with allergic rhinitis, whether it's seasonal or perennial.
• Prophylactic treatment for seasonal allergic rhinitis.
• Management of bronchial asthma and bronchitis.